Previous - 3.5 Evaporation

 

3.6 Analysis of crude product

Step by Step:

  1. TLC the crude product to make sure it matches the reaction mixture. If it does not, see TLC Troubleshooting.
  2. If you do not expect reagent peaks to overwhelm product peaks, take an NMR of your crude reaction mixture after workup.
  3. Why take a crude NMR or GC?
  4. If you observe two products and can identify them by NMR or GC, record the ratio of the products.
  5. Decide whether the product(s) are worth isolating: if so, proceed to Purification.


TLC
Crude NMR spectrum
Select best method for purification
Save a reference sample

 

Next Chapter - 4. PURIFICATION