Publications

39: Iron-Catalyzed Radical Intermolecular Addition of Unbiased Alkenes to Aldehydes


Mar Saladrigas, Jordi Puig, Josep Bonjoch*, and Ben Bradshaw*

Org. Lett.; 202022, 8111–8115 
doi.org/10.1021/acs.orglett.0c03081



38: Decahydroquinoline Ring 13C NMR Spectroscopic Patterns for the Stereochemical Elucidation of Phlegmarine-Type Lycopodium Alkaloids: Synthesis of (-)-Serralongamine A and Structural Reassignment and Synthesis of (-)-Huperzine K and (-)-Huperzine M (Lycoposerramine Y)


Caroline Bosch, Ben Bradshaw* and  Josep Bonjoch*

J. Nat. Prod; 2019, 82, 1576–1586.

37: Iron Hydride Radical Reductive Alkylation of Unactivated Alkenes


Mar Saladrigas, Josep Bonjoch*, and Ben Bradshaw*
Org. Lett.; 202022, 684–688 
doi.org/10.1021/acs.orglett.9b04459



36: Mechanistic Study on the Asymmetric Synthesis of the Wieland-Miescher Ketone and Analogs


Chunhui Liu, Ben Bradshaw, Feliu Maseras, Josep Bonjoch, Maria Besora

ChemCatChem., 201922, 684–688 
DOI: 10.1002/cctc.201900543



35: Hydrogen Atom Transfer (HAT)-Triggered Iron-Catalyzed Intra- and Intermolecular Coupling of Alkenes with Hydrazones: Access to Complex Amines.

Mar Saladrigas, Guillem Loren, Josep Bonjoch*, and Ben Bradshaw*
ACS Catalysis; 2018,  8, 11699-11703 
doi/10.1021/acscatal.8b03794



34: Synthesis of cis-hydrindan-2,4-diones bearing an all-carbon quaternary center by a Danheiser annulation

Gisela V Saborit, Carlos Cativiela, Ana I Jiménez, Josep Bonjoch*, and Ben Bradshaw*

Beilstein J. Org. Chem; 2018 ; 14: 2597–2601.
10.3762/bjoc.14.237



33: Radical Cyclization of Alkene-Tethered Ketones Initiated by Hydrogen-Atom Transfer.

Mar Saladrigas  Caroline Bosch  Gisela V. Saborit  Josep Bonjoch*, Ben Bradshaw*
Angew. Chem. Int. Ed., 2018, 57, 182-186.
10.1002/anie.201709659



32: A One-Pot Methodology for the Synthesis of the Yohimban Skeleton 

Claudio Parra, Pablo Solís, Josep Bonjoch *, Ben Bradshaw* 
Synlett.,
 2017; 28,  1753-1757.

10.1055/s-0036-1589092



31: The evolution of a stereoselective synthesis of the C1-C16 fragment of bryostatins 

Matthew Ball, Anne Baron, Ben Bradshaw, Raphaël Dumeunier, Matthew O'Brien and Eric J. Thomas*

Org. Biomol. Chem., 2016, 14, 9650-9681 
10.1039/C7OB02129A



30: Asymmetric synthesis of octahydroindoles via a domino robinson annulation/5-endo intramolecular aza-michael reaction 

Claudio Parra, Caroline Bosch, Enrique Gómez-Bengoa, Josep Bonjoch*, and Ben Bradshaw*
Special issue on heterocycles
J. Org. Chem., 2016, 81 (21), pp 10172–10179 
doi.org/10.1021/acs.joc.6b01568



29: Fischer indole reaction in batch and flow employing a sulfonic acid resin: synthesis of pyrido[2,3-a]carbazoles 

Caroline Bosch , Pablo López-Lledó , Josep Bonjoch*, Ben Bradshaw, Pieter J. Nieuwland, Daniel Blanco-Ania and Floris P. J. T. Rutjes*
2016, Volume 6, Issue 3, pp 240–243.
 https://doi.org/10.1556/1846.2016.00016


28: Synthesis of Serralongamine A and the Revised Structure of Huperzine N 

Gisela V. Saborit, Caroline Bosch, Teodor Parella, Ben Bradshaw*, and Josep Bonjoch*
2016, 81 (6), pp 2629–2634 
doi.org/10.1021/acs.joc.6b00025



27: Approach to cis-Phlegmarine Alkaloids via Stereodivergent Reduction: Total Synthesis of (+)-Serratezomine E and Putative Structure of (−)-Huperzine N

Caroline Bosch, Béla Fiser, Enrique Gómez-Bengoa, Ben Bradshaw*, and Josep Bonjoch*
2015, 17 (20), pp 5084–5087. 
 10.1021/acs.orglett.5b02581


26: Synthesis of the all-cis-trimethyldecalin fragment of unusual terpenes by radical-mediated protonolysis of an alkylboron derivative

Giorgio Villa, Ben Bradshaw, Cédric Bürki, Josep Bonjoch, Philippe Renaud
2014, Volume 55, Issue 33, 13, Pages 4608-4611.
https://doi.org/10.1016/j.tetlet.2014.06.075

25: Gram-scale Route to Phlegmarine Alkaloids: rapid total synthesis of (-)-Cermizine B.  

Ben Bradshaw,* Carlos Luque-Corredera and Josep Bonjoch*
2014, 50, 7099-7102 (cover issue)
https://doi.org/10.1039/C4CC01708K


24: Synthetic approaches towards the Lycopodium alkaloids


Ben Bradshaw, Gisela Saborit-Villarroya, Carlos Luque-Corredera, Marta Balañà and Josep Bonjoch
Recent Advances in Pharmaceutical Sciences IV, 2014: 143-163

ISBN: 978-81-308-0554-2 pdf


23: Total Synthesis of Aignopsanes, a New Class of Sesquiterpenes: (+)-Aignopsanoic Acid A, (-)-Methyl Aignopsanoate A, and (-)-Isoaignopsanoic A 

Dr. Cédric Bürki Prof. Josep Bonjoch Dr. Ben Bradshaw Dr. Giorgio Villa Prof. Philippe Renaud
Volume 21, Issue1 January 2, 2015 Pages 395-401.
 https://doi.org/10.1002/chem.201404766


22: Organocatalyzed asymmetric synthesis of morphans 

Ben Bradshaw*, Claudio Parra, and Josep Bonjoch*
2013, 15 (10), pp 2458–2461.
 https://doi.org/10.1021/ol400926p



21: Synthetic and DFT studies towards a unified approach to phlegmarine alkaloids: aza-Michael intramolecular processes leading to 5-oxodecahydroquinolines 

Ben Bradshaw, Carlos Luque-Corredera, Gisela Saborit, Carlos Cativiela, Ruth Dorel, Carles Bo, Josep Bonjoch
Volume 19, Issue 41 October 4, 2013 Pages 13881-13892.
https://doi.org/10.1002/chem.201301715



20: cis-Decahydroquinolines via Asymmetric Organocatalysis: Application to the Total Synthesis of Lycoposerramine Z

Ben Bradshaw*, Carlos Luque-Corredera, and Josep Bonjoch* 
2013, 15 (2), pp 326–329.
https://doi.org/10.1021/ol303257y


19: The Wieland-Miescher Ketone: A Journey from Organocatalysis to Natural Product Synthesis 

Bradshaw Ben. Bonjoch Josep. 
Synlett 2012(3): 337-356
DOI: 10.1055/s-0031-1290107



18: Synthesis of (S)-8a-methyl-3,4,8,8a-tetrahydro-1,6-(2H,7H-naphthalenedione via N-tosyl-(Sa)-binam-L-prolinamide organocatalysis

Ben Bradshaw, Gorka Etxebarria-Jardí, Josep Bonjoch, Santiago F. Viózquez, Gabriela Guillena, and Carmen Nájera
Org. Synth. 2011, 88, 330
DOI: 10.15227/orgsyn.088.0330



17: (Sa,S)-N-[2´-(4-methylsulfonoamido)-1,1´-binaphthyl-2-yl]pyrrolidine-2-carboxamide: an organocatalyst for the direct aldol reaction.  

Santiago F. Viózquez, Gabriela Guillena, Carmen Nájera, Ben Bradshaw, Gorka Etxebarria-Jardi, and Josep Bonjoch
Org. Synth. 2011, 88, 317
DOI: 10.15227/orgsyn.088.0317


16: Synthesis of 2-azabicyclo[3.3.1]nonane 

Josep Bonjoch*, Faïza Diaba, Ben Bradshaw
Synthesis 2011(7): 993-1018.
DOI: 10.1055/s-0030-1258420


15: Total synthesis of (-)- anominine 

Ben Bradshaw*, Gorka Etxebarria-Jardí and Josep Bonjoch*
2010, 132 (17), pp 5966–5967.
 https://doi.org/10.1021/ja101994q


14: Efficient solvent-free robinson annulation protocols for the highly enantioselective syntheis of the Wieland-Miescher ketone and analogues 

Ben Bradshaw, Gorka Etxebarría-Jardi, Josep Bonjoch*, Santiago F. Viózquez, Gabriela Guillena, Carmen Nájera
Volume 351, Issue 14-15 October 2009, Pages 2482-2490.
https://doi.org/10.1002/adsc.200900321


13: Fischer indolization of octahydroindol-6-one derivatives revisited: diastereoisomerization and racemization processes 

Mar Borregán, Ben Bradshaw, Nativitat Valls, Josep Bonjoch
Tetrahedron: Asymmetry 2008, 19, 2130-2134
https://doi.org/10.1016/j.tetasy.2008.09.009


12: Stereodivergent reduction of enelactams embedded in hexahydroindoles. Synthesis of trans-3-substituted-cis-3a-methyloctahydroindoles

Alejandro Cordero-Vargas, Ben Bradshaw, Josep Bonjoch*
200864, 8134-8140.
https://doi.org/10.1016/j.tet.2008.06.055


11: Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M3) receptors 

Benjamin Bradshaw, Paul Evans, Jane Fletcher, Alan T. L. Lee, Paul G. Mwashimba, Daniel Oehlrich, Eric J. Thomas,* Robin H. Davies, Benjamin C. P. Allen, Kenneth J. Broadley, Amar Hamrounic and
Christine Escargueil

Org. Biomol. Chem. 2008, 6, 2138-2157.
https://doi.org/10.1039/B801206


10: Polycyclic framework synthesis of anominine and tubingensin A indole diterpenoids

Ben Bradshaw, Gorka Etxebarria-Jardí and Josep Bonjoch*
2008, 6, 772-778.
https://doi.org/10.1039/B718280E


09: A preliminary evaluation of a metathesis approach to bryostatins

Matthew Ball, Benjamin J. Bradshaw, Raphaël Dumeunier, Thomas J.Gregson, Somhairle MacCormick, Hiroki Omori, Eric J. Thomas*
2006, 47, 2223-2227.
https://doi.org/10.1016/j.tetlet.2006.01.097


08: Approaches to the stereoselective total synthesis of biologically active natural products. 

Anne Baron, Matthew Ball , Benjamin Bradshaw, Sam Donnelly, Olivier Germay, Pilar C. Oller, Naresh Kumar, Nathaniel Martin, Matthew O’Brien, Hiroki Omori, Christopher Moore, Eric J. Thomas
Pure Appl. Chem., 2005, 77, 103–117,
DOI: 10.1351/pac200577010103
pdf



07: Enantioselective Syntheses of (+)-Xylarenal A and ent- Xylarenal A 

Sandra Díaz, Asensio González, Ben Bradshaw, Javier Cuesta, and Josep Bonjoch*
2005, 70 (9), pp 3749–3752.
https://doi.org/10.1021/jo0502450


06: A stereoselective synthesis of the C(1)-C(16) fragment of the bryostatins.  

Matthew Ball, Anne Baron, Benjamin Bradshaw, Hiroki Omori, Somhairle MacCormick, Eric J.Thomas
J. Org. Chem., 2004, 45, 8737-8740.
https://doi.org/10.1016/j.tetlet.2004.09.124


05: Synthesis of 1,3-dithiol-2-ones as proligands related to molybdopterin.

Ben Bradshaw, David Collison, C. David Garner and John A. Joule*
Org. Biomol. Chem. 2003, 1, 129-133.
https://doi.org/10.1039/B209217D

04: Synthesis of the organic ligand of the molybdenum cofactor, in protected form.

Ben Bradshaw, Andrew Dinsmore, Wadi Ajana, David Collison, C. David Garner and John A. Joule*
J. Chem. Soc., Perkin Trans. 1, 2001, 0 , 3239-3244. 
https://doi.org/10.1039/B108579B



03: The synthesis of pyrano[2,3-b]quinoxalines related to molybdopterin.  

Ben Bradshaw, Andrew Dinsmore, David Collison, C. David Garner and John A. Joule*
J. Chem. Soc., Perkin Trans. 1, 2001, 0, 3232-3238.
https://doi.org/10.1039/B108576J


02: Stable pyrano[2,3-b]quinoxalines and pyrano[2,3-g]pteridines related to molybdopterin.

Ben Bradshaw, David Collison, C. David Garnera and John A. Joule*  

1998, 0, 417-418

https://doi.org/10.1039/B008544H


01: Synthesis of a cobalt complex of a pyrano[2,3-b]quinoxaline-3,4-dithiolate related to molybdopterin.

Ben Bradshaw, Andrew Dinsmore, C. David Garner and John A. Joule*
1998, 0, 417-418 https://doi.org/10.1039/A708366A